PHARMACEUTICAL COMPOSITION OF PIPERACILLIN SODIUM AND SULBACTAM SODIUM

摘要

Disclosed is a pharmaceutical composition of piperacillin sodium and sulbactam sodium, comprising 2-4 parts by weight of piperacillin sodium and 1 part by weight of sulbactam sodium having a specific rotation of +230° to +235°. By optimizing the process for preparing sulbactam sodium, sulbactam sodium with the specific rotation of +230° to +235° is prepared, and the process for preparing piperacillin sodium is optimized, wherein same is beneficial for improving the stability of the pharmaceutical composition and the use thereof is safer.