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POLY(DIOL FUMARATES) AND POLY(DIOL FUMARATE-CO-SUCCINATES)

机译:聚(二甲苯烟酸酯)和聚(富马酸酯-二硫酸酯)

摘要

The disclosure relates to a class of diol-based, unsaturated aliphatic polyesters that biodegrade into monomers capable of mitigating infection. These poly(diol fumarates) (PDFs) and poly(diol fumarate-co-succinates) (PDFSs), can be crosslinked to form networks of scaffolds with antimicrobial degradation products. Both the diol carbon length and the degree of available double bonds are tunable, resulting in a highly controllable class of antimicrobial polymers useful for cell scaffolds and drug delivery systems and devices.
机译:本公开涉及一类基于二醇的不饱和脂族聚酯,其可生物降解为能够减轻感染的单体。这些聚富马酸二醇酯(PDFs)和聚富马酸二醇酯-共琥珀酸酯(PDFSs)可以交联形成具有抗菌降解产物的支架网络。二醇碳长度和可用双键的程度都是可调的,从而产生了高度可控的一类抗微生物聚合物,可用于细胞支架和药物递送系统及装置。

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