PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA SELECTIVE AGONISTS FOR INHIBITION OF RETINAL PIGMENT EPITHELIUM DEGENERATION OR GEOGRAPHIC ATROPHY

摘要

The invention provides a solution to the clinical problem of retinal pigment epithelium (RPE) degeneration or geographic atrophy (GA) associated with AMD. PPARϒ selective agonists, e.g., troglitazone and analogs thereof are used to reduce or inhibit RPE degeneration, GA, and/or the progression of dry AMD.