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PPAR AGONIST OR LXR AGONIST FOR USE IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS BY MODULATION OF LAP ACTIVITY
PPAR AGONIST OR LXR AGONIST FOR USE IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS BY MODULATION OF LAP ACTIVITY
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机译:PPAR激动剂或LXR激动剂,用于通过调节LAP活性来治疗系统性红斑狼疮
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摘要
Compositions and methods are provided for modifying diagnosing and treating inflammatory disease. The methods and compositions can be used to ameliorate the effects of a deficiency in the LAP pathway for clearing dead cells. Thus, methods are further provided for modulating dead cell clearance using an effective amount of a pharmaceutical composition that targets the LAP pathway. Accordingly, pharmaceutical compositions that target the LAP pathway re provided herein. The methods and compositions described herein can be used to treat inflammatory disease, such as systemic lupus erythematosus (SLE).
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