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METHOD FOR DIAGNOSING TUBERCULOSIS USING ANTIBODY REACTION DETECTION AGAINST TUBERCULOSIS-SPECIFIC ANTIGEN

机译:结核特异性抗原的抗体反应检测诊断结核的方法

摘要

Disclosed are a method for discriminating active, latent, or recurrent tuberculosis, in particular for diagnosing or detecting whether a specimen determined as a negative in a sputum smear examination is an active tuberculosis or not by using a specific reaction of a specimen to combination of antigens selected from 38 kDa, 16 kDa, ESAT-6, CFP-10, and LAM antigens, and a kit. The method or kit according to the present invention can diagnose whether a sputum smear negative specimen is active, latent or recurrent tuberculosis which is difficult to diagnose through the typical method with a high sensitivity and specificity, and thus the present invention can accurately and rapidly determine tuberculosis alone or in combination with the typical smear method.;COPYRIGHT KIPO 2016
机译:公开了一种鉴别活动性,潜伏性或复发性结核病的方法,特别是通过使用标本对抗原结合的特异性反应来诊断或检测在痰涂片检查中被确定为阴性的标本是否为活动性结核病。选自38 kDa,16 kDa,ESAT-6,CFP-10和LAM抗原以及试剂盒。根据本发明的方法或试剂盒可以诊断痰涂片阴性样本是否为活动性,潜伏性或复发性结核病,这很难通过典型方法以高灵敏度和特异性进行诊断,因此本发明可以准确,快速地确定结核病单独或与典型涂片检查法结合使用;; COPYRIGHT KIPO 2016

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