The present invention relates to a two-phase reaction system and a production method thereof. According to the present invention, in the production of long chain retinyl ester via transesterification using short chain retinyl ester and long chain carboxylic acid, it is possible to produce high purity long chain retinyl ester by increasing the turnover rate in the transesterification using the two-phase reaction system made of an organic solvent phase and an aqueous solution phase.;COPYRIGHT KIPO 2016
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