首页> 外国专利> 3- 3- Promoter systems induced by 3-hydroxypropionic acid and method for production of 3-hydroxypropionic acid using the same

3- 3- Promoter systems induced by 3-hydroxypropionic acid and method for production of 3-hydroxypropionic acid using the same

机译:3- 3-由3-羟基丙酸诱导的促进剂系统和使用该系统的生产3-羟基丙酸的方法

摘要

The present invention relates to a promoter system for inducing expression by 3-hydroxypropionic acid, and to a method for biologically producing 3-hydroxypropionic acid by using the same. It is needed to continuously produce new enzymes having enzyme activities to biologically improve 3-HP production. As a result of screening promoters and transcription regulators reacting with 3-HP in various microorganisms including P. denitrificans, it has been clarified that a LysR protein and a specific gene base sequence bound with the protein constitute the same. Accordingly, a 3-HP inducing system according to the present invention is expected to be effectively used in adjusting a 3-HP metabolic pathway.
机译:本发明涉及通过3-羟基丙酸诱导表达的启动子系统,并涉及使用该启动子系统生物生产3-羟基丙酸的方法。需要连续生产具有酶活性的新酶以生物学上提高3-HP的产量。由于在包括反硝化假单胞菌在内的多种微生物中筛选了与3-HP反应的启动子和转录调节剂,因此已经阐明,LysR蛋白和与该蛋白结合的特定基因碱基序列构成相同的。因此,期望根据本发明的3-HP诱导系统有效地用于调节3-HP代谢途径。

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