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3- 3- Promoter systems induced by 3-hydroxypropionic acid and method for production of 3-hydroxypropionic acid using the same

机译：3- 3-由3-羟基丙酸诱导的促进剂系统和使用该系统的生产3-羟基丙酸的方法

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摘要

The present invention relates to a promoter system in which expression is induced by 3-hydroxypropionic acid, and a biological production method of 3-hydroxypropionic acid using the promoter system. In order to improve biologically 3-HP production, . Screening of the transcriptional regulators and promoters responsive to 3-HP in various microorganisms including Pseudomonas denitrificans revealed that the LysR protein and a specific gene sequence that binds to this protein . Thus, the 3-HP inducible system according to the present invention is expected to be effectively used to regulate the 3-HP metabolic pathway.

机译：本发明涉及其中通过3-羟基丙酸诱导表达的启动子系统，以及使用该启动子系统的3-羟基丙酸的生物生产方法。为了提高3-HP的生物产量，在包括假单胞菌（Pseudomonas denitrificans ）在内的多种微生物中筛选了对3-HP有响应的转录调节子和启动子，发现了LysR蛋白和与该蛋白结合的特定基因序列。因此，期望根据本发明的3-HP诱导系统有效地用于调节3-HP代谢途径。 展开▼

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公开/公告号KR101877303B1

专利类型

公开/公告日2018-07-11

原文格式PDF

申请/专利权人 (주)노루홀딩스;주식회사 노루알앤씨;
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申请/专利号KR20160073091

发明设计人 박성훈;저우성팡;아속 소마순다;설은희;아이날라 사티쉬쿠마;
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申请日2016-06-13

分类号C12N15/78;C12P7/42;

国家 KR

入库时间 2022-08-21 12:37:29

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