首页> 外国专利> HMG-CoA LLP5273 LACTOBACILLUS PLANTARUM LLP5273 STRAIN HAVING INHIBITION ABILITY OF BILE ACID AND HIGH INIBITION ACTIVITY TO HMG-CoA REDUCTASE IN LIVER CELL AND USES THEREOF

HMG-CoA LLP5273 LACTOBACILLUS PLANTARUM LLP5273 STRAIN HAVING INHIBITION ABILITY OF BILE ACID AND HIGH INIBITION ACTIVITY TO HMG-CoA REDUCTASE IN LIVER CELL AND USES THEREOF

机译:HMG-CoA LLP5273扁平乳杆菌LLP5273菌株具有抑制胆汁酸的能力,并且对肝细胞中HMG-CoA还原酶具有高诱导活性,并利用其

摘要

The present invention relates to Lactobacillus plantarum LLP5273, which is novel lactobacillus separated from kimchi. The Lactobacillus plantarum LLP5273 has an excellent decomposition ability with respect to composite bile acid, acid resistance, and biliary resistance, thereby safely reaching the intestines. Also, when the Lactobacillus plantarum LLP5273 is manufactured as a fungus crushing material and treated in liver cells, the Lactobacillus plantarum LLP5273 has a significant inhibition ability to HMG-CoA reductase which is one of the main enzymes involved in cholesterol synthesis.
机译:本发明涉及植物乳杆菌LLP5273,其是从泡菜中分离的新型乳杆菌。植物乳杆菌LLP5273相对于复合胆汁酸,抗酸性和胆汁抗性具有优异的分解能力,从而安全地到达肠。另外,当植物乳杆菌LLP5273被制造为真菌压碎材料并在肝细胞中处理时,植物乳杆菌LLP5273对HMG-CoA还原酶具有显着的抑制能力,所述HMG-CoA还原酶是参与胆固醇合成的主要酶之一。

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