首页> 外国专利> ATR 2--6--N-5---3--15-A-3- RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-5-FLUORO-PYRIDIN-3-YL- PYRAZOLO15-APYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

ATR 2--6--N-5---3--15-A-3- RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-5-FLUORO-PYRIDIN-3-YL- PYRAZOLO15-APYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF

机译:2-氨基-6-氟-N- [5-氟-吡啶-3-基]的ATR 2--6--N- [5 --- 3-]-[15-A] -3-放射标记的衍生物]-吡唑并[15-A]嘧啶-3-氨基甲酸酯化合物,可作为ATR激酶抑制所述化合物和其不同固体形式的制备

摘要

The present invention relates to compounds useful as inhibitors of ATR protein kinases. The present invention provides a pharmaceutical composition comprising a compound of the invention; Methods of treating various diseases, disorders, and conditions using the compounds of the present invention; A method for producing the compound of the present invention; An intermediate for the preparation of a compound of the invention; And solid forms of the compounds of the present invention. The compounds of the present invention have formula (I-1) or (IA) Formula I-1 In the above formulas, The variables are as defined herein.
机译:本发明涉及用作ATR蛋白激酶抑制剂的化合物。本发明提供了包含本发明化合物的药物组合物。使用本发明的化合物治疗各种疾病,病症和病状的方法;本发明化合物的制备方法;用于制备本发明化合物的中间体;和本发明化合物的固体形式。本发明的化合物具有式(I-1)或(IA)式I-1 <在上式中,变量如本文所定义。

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