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18F- THE COMPOSITION FOR STABLIZIING RADIOCHEMICAL PURITY OF 18Ffluoro-DOPA AND METHOD FOR PREPARING THE SAME
18F- THE COMPOSITION FOR STABLIZIING RADIOCHEMICAL PURITY OF 18Ffluoro-DOPA AND METHOD FOR PREPARING THE SAME
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机译:[18F]-稳定[18F]氟-DOPA的放射化学纯度的组合物及其制备方法
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摘要
The present invention relates to a composition for stabilizing radiochemical purity of [fluorine-18]fluorodopa by suppressing the generation of impurities for a fixed amount of time, and to a preparation method thereof. The composition according to the present invention comprises [fluorine-18]fluorodopa; ethanol with a concentration of 5-30% (V/V) based on the total composition; and a buffer having a pKa value of 6-8.1 at 25C. Thus, the composition suppresses generation of impurities for a fixed amount of time, and stabilizes the radiochemical purity of the [fluorine-18]fluorodopa.
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