MULTIPLE TANDEM SERIES HAIRPIN DNA CAPABLE OF CANCER CELL-SELECTIVE DRUG DELIVERY, AND USE THEREOF AS DRUG CARRIER

摘要

The present invention relates to an amphipathic nucleic acid molecule where a hydrophobic material-DNA zygote and a target ligand-DAN zygote form a base pair on multiple tandem hairpin DNA polymer, a nucleic acid composite including the same, and a use thereof as a drug carrier. The drug carrier of the present invention is capable of selectively delivering drugs to a target cell and a target tissue, does not have cytotoxicity, and can effectively discharge the drugs to the cytoplasm after being permeated into cells, thereby being utilized in a cancer treatment agent, and a screening method for cell-based drugs.;COPYRIGHT KIPO 2017