BCP-BASED MICROCHANNEL SYRINGE TYPE BONE GRAFT MATERIAL IN WHICH ANTIBIOTICS AND GROWTH FACTOR ARE LOADED

摘要

The present invention is designed for bone defects due to the infection or for bone defects due to the infection during a recovery period after a surgery. Porous BCP granules are coated with bio-polymers for delivering BMP-2 growth factors, and thereby are capable of continuous discharge. Three types of biopolymers such as collagen, heparin, and dopamine are used to deliver BMP-2, and gelatin and hyaluronic acid-gelatin microspherical granules are used as a carrier for loading antibiotics. The porous BCP granules and the gelatin and hyaluronic acid-gelatin granules for loading the growth factors and antibiotics are used as injectable carriers by adding hyaluronic acid.;COPYRIGHT KIPO 2017