首页> 外国专利> 1 2--55--6--6--3456- 2-AMINO-55-DIFLUORO-6-FLUOROMETHYL-6-PHENYL-3456-TETRAHYDROPYRIDINES AS BACE1 INHIBITORS

1 2--55--6--6--3456- 2-AMINO-55-DIFLUORO-6-FLUOROMETHYL-6-PHENYL-3456-TETRAHYDROPYRIDINES AS BACE1 INHIBITORS

机译:1 2--55--6--6--3456- 2-氨基-55-二氟-6-氟甲基-6-苯基-3456-四氢吡啶作为BACE1抑制剂

摘要

The present invention relates to compounds of formula I which are inhibitors of the BACE1 enzyme. Individual aspects of the present invention are directed to pharmaceutical compositions comprising such compounds and to the use of the compounds for the treatment of disorders wherein reduction of A [beta] deposits is beneficial, such as Alzheimer's disease, (I) .
机译:本发明涉及作为BACE1酶抑制剂的式I化合物。本发明的各个方面涉及包含这样的化合物的药物组合物,以及该化合物在治疗疾病中的用途,其中减少Aβ沉积是有益的,例如阿尔茨海默氏病(I)。

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