BCL XL BCL XL INHIBITORY COMPOUNDS HAVING LOW CELL PERMEABILITY AND ANTIBODY DRUG CONJUGATES INCLUDING THE SAME

摘要

The present invention relates to a Bcl-xL inhibitor with low cellular permeability, an antibody drug conjugate (ADC) comprising said inhibitor, a composition comprising a synthon, inhibitor or ADC useful for the synthesis of ADCs, and a variety of inhibitors and ADCs And a method of using the same.