COMPOSITION COMPRISING ROSMARINIC ACID AS ACTIVE INGREDIENT FOR PREVENTING, AMELIORATING OR TREATING COLORECTAL CANCER

摘要

The present invention relates to a pharmaceutical composition comprising rosmarinic acid as an active ingredient for preventing, ameliorating or treating colorectal cancer. The composition according to the present invention, in a CT26 cell which is a mouse-derived metastatic colorectal cancer cell line, retains properties of preventing, ameliorating or treating colorectal cancer through the efficacy of inducing apoptosis and regulating cell cycle. The composition according to the present invention retains properties of improving or treating the metastasis of colorectal cancer through the efficacy of inhibiting the metastatic ability of the colorectal cancer by regulating an epithelium-mesenchyma conversion factor, a migrating/invasive factor and an AMPKα activator.;COPYRIGHT KIPO 2017