Composition for use in increasing engraftment efficiency of hematopoietic stem cells after transplantation

摘要

The present invention includes at least one dipeptidyl peptidase-IV (DPP-IV) inhibitor for increasing the migration and homing of hematopoietic progenitor cells in stem cell transplant recipients As a new use of the composition, the hematopoietic stem and / or progenitor cells are treated with an engraftment enhancing compound, specifically a prostacyclin analogue and a cAMP enhancer, prior to transplantation, / RTI in vitro.