NOVEL USE OF COMPOSITION CONTAINING KLOTHO IN TACROLIMUS-INDUCED RENAL CELLULAR TOXICITY

摘要

The present invention relates to a pharmaceutical composition for inhibiting tacrolimus-induced renal toxicity, or preventing or treating mitochondrial diseases containing a composition comprising Klotho as an active ingredient. The Klotho compound shows a protection effect with respect to mitochondria damage in renal cells induced by tacrolimus which is an immunosuppressant, thereby improving renal functions. Accordingly, the Klotho compound can be used as a transplant disease medicine as an antiaging functional agent and is effective in mitochondria-related diseases.;COPYRIGHT KIPO 2017