Anti-thrombotic composition comprising serine protease extracted from Diopatra Sugokai

摘要

The present invention relates to an anti-thrombotic composition, a pharmaceutical composition for preventing or treating thrombotic diseases and a food composition for preventing or alleviating thrombotic diseases comprising serine protease extracted from Diopatra sugokai. The serine protease according to the present invention shows not only direct and indirect thromboclastic abilities but anticoagulant effects and cell stability and can overcome side effects such as reocclusion of tissue-plasminogen activator (t-PA) which is solely used as a thrombolytic agent, thereby being usefully used as an anti-thrombotic pharmaceutical composition and a food composition which are effective in diseases such as hypertension, a cardiac disease, stroke, myocardial infarction, etc. caused by thrombus and cohesion of platelet.