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Methods for Selecting Improved Stem Cell for Treating Intraventricular Hemorrhage of Premature Infants
Methods for Selecting Improved Stem Cell for Treating Intraventricular Hemorrhage of Premature Infants
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机译:选择改良干细胞治疗早产儿脑室内出血的方法
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摘要
The present invention relates to a high efficacy stem cell selection method for treating cerebrovascular diseases, including a step for measuring a level of nerve growth factors. The present invention further relates to a high efficacy stem cell selected by the method. According to the present invention, brain-derived neurotrophic factor (BDNF) secreted by mesenchymal stem cells is involved in mediation of cell death, inflammation, astrogliosis, and prevention of development of hydrocephalus after hemorrhage, and plays a crucial role in ameliorating myelination after intraventricular hemorrhage. According to the present invention, the high efficacy stem cell selection method can be useful for treating various cerebrovascular diseases including intraventricular hemorrhage in newborns.
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