Methods for Selecting Improved Stem Cell for Treating Intraventricular Hemorrhage of Premature Infants

摘要

The present invention relates to a high efficacy stem cell selection method for treating cerebrovascular diseases, including a step for measuring a level of nerve growth factors, and to a high efficacy stem cell selected by the method. According to the present invention, brain-derived neurotrophic factor (BDNF) secreted by mesenchymal stem cells is involved in mediation of cell death, inflammation, astrogliosis, and prevention of development of hydrocephalus after hemorrhage, and plays a crucial role in ameliorating myelination after intraventricular hemorrhage. According to the present invention, the high efficacy stem cell selection method can be useful for treating various cerebrovascular diseases including intraventricular hemorrhage in newborns.