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Novel human gene crucial for the replication of influenza virus and use thereof

机译:对流感病毒复制至关重要的新型人类基因及其用途

摘要

The present invention relates to a novel human gene involved in the replication of an influenza virus and use thereof. More specifically, the present invention relates to a pharmacological composition for preventing or treating the influenza virus and a health functional food for preventing or treating the same based on an expression inhibitor of a gene TMPRSS9 involved in the replication of the influenza virus, an activation inhibitor of a protein TMPRSS9, or a mixture thereof as an active ingredient. The present invention relates to a method for screening an antiviral drug against the influenza virus by estimating the mRNA of the gene TMPRSS9 or the protein level thereof.
机译:本发明涉及一种涉及流感病毒复制的新型人类基因及其用途。更具体地,本发明涉及基于涉及流感病毒复制的基因TMPRSS9的表达抑制剂,激活抑制剂来预防或治疗流感病毒的药理组合物以及用于预防或治疗流感病毒的保健功能性食品。蛋白TMPRSS9或其混合物作为有效成分。本发明涉及通过估计基因TMPRSS9的mRNA或其蛋白水平来筛选针对流感病毒的抗病毒药物的方法。

著录项

  • 公开/公告号KR101693243B1

    专利类型

  • 公开/公告日2017-01-05

    原文格式PDF

  • 申请/专利权人 INSTITUT PASTEUR KOREA;

    申请/专利号KR20160074744

  • 发明设计人 MIN JI YOUNG;LEE JI HYE;SHIN DONG JO;

    申请日2016-06-15

  • 分类号A61K48;A23L1/30;A61K39/395;C12Q1/68;G01N33/50;G01N33/68;

  • 国家 KR

  • 入库时间 2022-08-21 13:26:16

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