COMPOSITION FOR PREDICTING RISK OF PREMATURE BIRTH BY DETECTING CHANGES IN CpG METHYLATION OF GENES AND USE THEREOF

摘要

The present invention relates to a composition for diagnosing the risk of premature birth by detecting the level of methylation on CpG regions of genes in a specimen of a pregnant patient. The present invention further relates to a diagnostic kit and a diagnostic method for diagnosing the risk of premature birth. To this end, the composition includes at least one preparation selected from the group consisting of microRNA-886 (mir-886) and INS-IGF2 readthrough for measuring the level of methylation on the CpG regions of genes of the patient.;COPYRIGHT KIPO 2017