Novel pazopanib derivatives and pharmaceutical composition comprising the same

摘要

The present invention relates to a novel pazopanib derivative or salt thereof having both an angiogenesis inhibitory activity and an epithelial growth factor inhibitory activity, and a pharmaceutical composition containing the same as an active ingredient. The pazopanip derivative is different from pazopanib Inhibition of angiogenesis inhibitory activity and inhibits EGFR-related growth factor. Therefore, it is possible to treat and prevent EGFR-related cancer diseases such as lung cancer, colon cancer or breast cancer more effectively through a multi-target target. Especially, Can effectively treat and prevent non-small cell lung cancer.;