首页> 外国专利> SMALLPOX DNA VACCINE AND THE ANTIGENS THEREIN THAT ELICIT AN IMMUNE RESPONSE

SMALLPOX DNA VACCINE AND THE ANTIGENS THEREIN THAT ELICIT AN IMMUNE RESPONSE

机译:SMALLPOX DNA疫苗及其引发免疫反应的抗原

摘要

The present invention provides a kit comprising at least one DNA plasmid capable of producing a protective immune response against a poxvirus in a mammal and expressing a plurality of VACV MV antigens and at least one DNA capable of expressing a plurality of VACV EV antigens RTI ID = 0.0 plasmid. / RTI The present invention also relates to a method of inducing a protective immune response against a poxvirus in a mammal, including a neutralizing antibody response, comprising injecting said DNA vaccine into the tissue of a mammal.
机译:本发明提供了一种试剂盒,其包含至少一个能够在哺乳动物中产生针对痘病毒的保护性免疫应答并表达多种VACV MV抗原的DNA质粒,以及至​​少一种能够表达多种VACV EV抗原的DNA。 0.0>质粒。本发明还涉及在哺乳动物中诱导针对痘病毒的保护性免疫应答,包括中和抗体应答的方法,该方法包括将所述DNA疫苗注射到哺乳动物的组织中。

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