- LYCOPENE AND RESVERATROL COMPOSITIONS FOR NK CELL ACTIVATION RESULTING IN ANTI-NEOPLASTIC EFFECT

摘要

A composition comprising a therapeutically effective amount of a carotenoid and a terpenoid, which can be taken simultaneously or sequentially with a single agent or two separate agents to elevate the activity of natural killer (NK) cells during metabolic processes. Specifically, the composition contains lycopene and resveratrol in a molar ratio of 1:10 to 10: 1, more preferably in a molar ratio of 1: 1 to 3: 1, and most preferably 3: 1. On the other hand, the preferred ratio can be expressed in a weight ratio of 1: 4 to 25: 1, more preferably 2.5: 1 to 7.5: 1, and most preferably 7.5: 1. The composition may be formulated as a medicament, dietary supplement or food for oral administration and may be provided at a dose of about 3.5 mg per 20 g of the mammalian body weight in a therapeutically effective amount, preferably 2.5: 1, have. Which can be converted to doses of 400 mg to 1000 mg per day to a typical human in need of increased NK cell activity. Preferably, the therapeutically-effective aspects of the present compositions include metabolically produced preparations, prodrug or intermediate compounds of the present compositions useful for triggering NK cells to cytotoxic or cytolytic reactions.