首页> 外国专利> pH- PH-responsive nanoparticle using mussel adhesive protein for drug delivery and method for preparing the same

pH- PH-responsive nanoparticle using mussel adhesive protein for drug delivery and method for preparing the same

机译:使用贻贝粘附蛋白进行药物递送的pH-ph响应纳米颗粒及其制备方法

摘要

The present invention relates to a pH-responsive metal-catechol derivative nanoparticle, particularly Fe (III)-doped nanoparticle for drug delivery based on mussel adhesive protein, and a method for producing the same. Can be easily and rapidly penetrated into the target cell and can be easily and rapidly infiltrated into the target cell by using acidic conditions such as pH, pH, pH, and the like, by using the catechol derivative-metal complex, especially the dopa-Fe () complex, , It has the effect of selectively delivering the drug to a specific disease in an acidic environment.;
机译:本发明涉及基于贻贝粘附蛋白的pH响应性金属邻苯二酚衍生物纳米颗粒,特别是掺杂Fe(III)的纳米颗粒用于药物递送及其制备方法。通过使用酸性条件(例如pH,pH,pH等),并使用儿茶酚衍生物-金属络合物(尤其是多巴胺),可以轻松快速地渗透到靶细胞中,并且可以轻松快速地渗透到靶细胞中。 Fe()络合物,具有在酸性环境中选择性将药物递送至特定疾病的作用。

著录项

  • 公开/公告号KR101722503B1

    专利类型

  • 公开/公告日2017-04-04

    原文格式PDF

  • 申请/专利权人 포항공과대학교 산학협력단;

    申请/专利号KR20150035270

  • 发明设计人 정호균;김범진;차형준;

    申请日2015-03-13

  • 分类号A61K47/48;A61K31/704;A61K47/02;A61K47/42;

  • 国家 KR

  • 入库时间 2022-08-21 13:25:47

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号