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NKX6.3 Use of NKX6.3 for onset prediction early diagnosis and treatment of cancer

机译:NKX6.3 NKX6.3在癌症的发病预测,早期诊断和治疗中的用途

摘要

The present invention relates to the use of NKX6.3 as cancer prediction, early diagnosis and treatment, more specifically NKX6.3 It predicts cancer development through amount of protein expression, mRNA expression amount and DNA copy number, Diagnosis and treatment of cancer by administering an NKX6.3 protein or gene. Since NKX6.3 according to the present invention is inhibited in activity or expression in cancer cells, it can be used as a diagnostic composition capable of early diagnosis of cancer, and NKX6.3 it induces expression and inhibits survival and proliferation of cancer cells And exhibit a function of inducing apoptosis, which is useful as a composition for chemotherapy.;
机译:NKX6.3在癌症预测,早期诊断和治疗中的用途本发明涉及NKX6.3在癌症预测,早期诊断和治疗中的用途,更具体地讲,其通过蛋白质表达量,mRNA表达量和DNA拷贝数预测癌症发展,通过给药来诊断和治疗癌症。 NKX6.3蛋白或基因。由于根据本发明的NKX6.3在癌细胞中的活性或表达受到抑制,因此可以用作能够早期诊断癌症的诊断组合物,并且NKX6.3可以诱导癌细胞的表达并抑制其存活和增殖。表现出诱导细胞凋亡的功能,可用作化学疗法的组合物。

著录项

  • 公开/公告号KR101722836B1

    专利类型

  • 公开/公告日2017-04-18

    原文格式PDF

  • 申请/专利权人 가톨릭대학교 산학협력단;

    申请/专利号KR20150069359

  • 发明设计人 최원석;윤정환;박원상;

    申请日2015-05-19

  • 分类号A61K38/17;A61K38/16;A61K48/00;G01N33/50;

  • 国家 KR

  • 入库时间 2022-08-21 13:25:48

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