Method of screening compound for treating sepsis and pharmaceutical composition for treating sepsis

摘要

The present invention provides a method for screening a therapeutic agent for sepsis comprising the step of confirming the physical interaction of a nuclear HMGB1 protein and a SIRT1 protein and a pharmaceutical composition for treating sepsis comprising an activator of SIRT1 protein or SIRT1 protein.The screening method of the therapeutic agent for sepsis of the present invention can be effectively used as a screening method capable of effectively screening a therapeutic agent for sepsis, and the pharmaceutical composition for treating sepsis of the present invention can be effectively used as a therapeutic agent for sepsis.;