The present invention relates to a chewing gum formulation comprising antihistamine, and more specifically, to a chewing gum formulation comprising as an active ingredient: an antihistamine agent, which is one selected from cetirizine hydrochloride, astemizole, loratadine, and bepotastine hydrochloride; a gum base; at least one sweetening agent selected from xylitol, mannitol, erythritol, maltitol, sucralose, aspartame, and acesulfame potassium; at least one slip agent selected from magnesium stearate, stearic acid, sodium starch glycolate, colloidal silicon dioxide, and talc; and a flavoring agent. The present invention provides an antihistamine agent in the form of a chewing gum, which allows the drug to be processed rapidly inside the body and has an effect of masking bitterness at the same time. Also, since the drug is provided in the form of a chewing gum, side effects of antihistamine including somnolence, dryness of the mouth, and the like can be alleviated by masticatory movements.;COPYRIGHT KIPO 2017
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