ALGINATE OLIGOMERS FOR USE IN OVERCOMING MULTIDRUG RESISTANCE IN BACTERIA

摘要

The present invention provides a method of overcoming one or more antibiotic resistance to multidrug resistant bacteria comprising contacting an alginate oligomer with an antibiotic to a multidrug resistant bacterium. Multidrug-resistant bacteria can be on biological or inanimate surfaces and provide medical and non-medical uses and methods. In one aspect, the invention is directed to a method of treating a subject suffering from a multidrug-resistant bacterial infection, susceptible to an infection, or at risk of infection, by dissolving the antibiotic resistance of the multidrug- Lt; RTI ID = 0.0 oligomer / RTI In another aspect, the method can be used for the purpose of eradicating, e.g. disinfecting and removing, contaminants with multidrug-resistant bacteria.