- Method for measuring cell-to-cell transmission of -synuclein aggregates using bimolecular fluorescence complementation system and screeing method of a substance for preventing or treating neurodegenerative disease using the same

摘要

The present invention is dual to measure the transition between neurons of protein aggregates-cell cell model and a pretty little relates to a nematode (Caenorhabditis elegans) model system, more particularly to a fluorescent protein N- terminal or C- terminal alpha- It relates to sinyu way continuous interstitial transition measured in the clean aggregate, and a screening method of a substance for the prevention and treatment of neurodegenerative diseases - sinyu transformed cells and animal model systems, alpha using the same, each expressing a fusion protein of a clean protein .