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EC-SOD EC-SOD Recombinant EC-SOD gene optimized for plant expression and method for mass producing recombinant EC-SOD protein therefrom

机译:EC-SOD EC-SOD为植物表达而优化的重组EC-SOD基因和从其大量生产重组EC-SOD蛋白的方法

摘要

The present invention relates to a mass production method of the recombinant EC-SOD protein using an expression optimized recombinant EC-SOD gene from the plant, and this, and more particularly containing the expressed optimization of recombinant EC-SOD gene in plants, and this recombinant expression vector, the recombinant transformed with an expression vector conversion plant cells, tissues, part of the plant or the whole, and method of producing transgenic plants using the above recombinant expression vectors and recombinant EC-SOD mass production method of protein, and the method as it is for the inflammatory diseases and blood composition for the prevention or treatment of disease caused by start-containing mass produced recombinant EC-SOD protein as an active ingredient. Or more As described, by the present invention by using a manufacturing method using the same and an expression optimized recombinant EC-SOD gene in plants expressing high EC-SOD protein, the enzymatic activity that is not modified on the crops, such as tobacco according to the low cost, It can be effectively used for mass production by developing effective and safe therapeutic proteins in various inflammatory diseases and diseases caused by angiogenesis with high efficiency.;
机译:重组EC-SOD蛋白的大规模生产方法技术领域本发明涉及使用来自植物的表达优化的重组EC-SOD基因的重组EC-SOD蛋白的大量生产方法,更具体地,涉及在植物中表达的重组EC-SOD基因的表达优化。重组表达载体,用表达载体转化的重组体转化植物细胞,组织,植物的一部分或全部,以及使用上述重组表达载体和重组EC-SOD蛋白质的大量生产方法生产转基因植物的方法,以及方法,用于预防或治疗由开始大量生产的重组EC-SOD蛋白作为有效成分引起的疾病的炎症性疾病和血液组合物。如上所述,通过本发明,在表达高EC-SOD蛋白的植物中,通过使用其方法和表达优化的重组EC-SOD基因的制造方法,在烟草等农作物上未修饰酶活性。通过低成本,高效地开发各种炎症性疾病和由血管生成引起的疾病的安全有效的治疗性蛋白质,可以有效地用于批量生产。

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