ANIMAL AS MODELS FOR WOUND METHOD OF MANUFACTURING THEREOF AND METHOD OF ANALYZING EFFICACY OF WOUND THERAPEUTIC AGENT USING THEREOF

摘要

It is an object of the present invention to overcome the limitations that occur when a skin recovery process uses a mouse different from a human skin cell as a model of wound treatment research and to provide a wound treatment that can be applied to a wound treatment research in a realistic and economical manner The present invention relates to a method for producing an animal for a model, and a method for analyzing the efficacy of a wound treatment agent using the same.Therefore, the present invention relates to a method for manufacturing a wound-containing wound dressing comprising a natural material permeable hydrogel-containing wound dressing which is inserted into a cylindrical body perpendicularly to the surface of a wound dressing to suppress the horizontal construction ability peculiar to a rodent epithelium, Provide a therapeutic model.According to the present invention, it is possible to produce an animal model for an animal which does not inhibit immunity because it does not cause an immune response, and it is possible to study an agent for wound healing using an animal for a model more similar to a human wound environment is. In addition, the hydrogel is injected into the cylindrical body to form a thin film on the wound, thereby stably absorbing the sample and increasing the possibility of clinical application.;