首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF A LUNG DISEASE COMPRISING MESENCHYMAL STEM CELLS HAVING IMPROVED PROLIFERATION AND DIFFERENTIATION CAPACITY

PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF A LUNG DISEASE COMPRISING MESENCHYMAL STEM CELLS HAVING IMPROVED PROLIFERATION AND DIFFERENTIATION CAPACITY

机译:预防或治疗包含间充质干细胞的肺疾病的增生和分化能力得到改善的药物组合物

摘要

The present invention relates to a pharmaceutical composition for preventing or treating pulmonary disease comprising mesenchymal stem cells having improved proliferation and differentiation ability characterized by the presence or absence of expression of a specific cell marker, According to the method of the present invention, mesenchymal stem cells having excellent proliferation and differentiation ability can be easily obtained from mesenchymal stem cells obtained from various sources based on the presence or absence of expression of CD26, CD49f, CD146 and EGFR. And the obtained mesenchymal stem cells can be usefully used for treating or preventing emphysema-bearing lung diseases.
机译:本发明涉及用于预防或治疗肺部疾病的药物组合物,其包含具有改善的增殖和分化能力的间充质干细胞,其特征在于是否存在特定细胞标志物的表达。根据本发明的方法,间充质干细胞具有或不具有CD26,CD49f,CD146和EGFR的表达,可以容易地从各种来源的间充质干细胞中得到具有优异的增殖和分化能力的细胞。并且获得的间充质干细胞可有效地用于治疗或预防患有肺气肿的肺部疾病。

著录项

  • 公开/公告号KR101779763B1

    专利类型

  • 公开/公告日2017-09-19

    原文格式PDF

  • 申请/专利权人 메디포스트(주);

    申请/专利号KR20160025484

  • 申请日2016-03-03

  • 分类号A61K35/28;A61K35/34;A61K35/35;A61K35/36;A61K35/48;A61K35/50;A61K35/51;C12N5/0775;

  • 国家 KR

  • 入库时间 2022-08-21 13:24:49

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