Method for searching candidate material for anti-cancer drug using localized surface plasmon resonance

摘要

The present invention relates to a method of searching for a candidate cancer drug, and more particularly, Analyzing a spectrum of gold nanoparticles on the substrate after binding proteins involved in cancer development and metastasis to obtain reference data; Binding a protein involved in cancer development and metastasis to gold nanoparticles on the substrate, adding a candidate substance inhibiting the activity of the protein, and analyzing the spectrum to obtain comparative data; And analyzing the reference data and the comparison data to read whether the candidate substance is an inhibitory substance against the activity of the protein.According to the present invention, it is possible to precisely and easily search candidates for inhibiting activity against a predetermined protein involved in cancer development and metastasis.;