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MICROORGANISM FOR METHIONINE PRODUCTION WITH IMPROVED METHIONINE SYNTHASE ACTIVITY AND METHIONINE EFFLUX
MICROORGANISM FOR METHIONINE PRODUCTION WITH IMPROVED METHIONINE SYNTHASE ACTIVITY AND METHIONINE EFFLUX
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机译:甲硫氨酸合成酶活性和甲硫氨酸流出改善的生产甲硫氨酸的微生物
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摘要
The present application is related to a recombinant microorganism optimized for the fermentative production of methionine and/or its derivatives, wherein in said recombinant microorganism, the cobalamin-dependent methionine synthase activity and the methionine efflux are enhanced. The application is also related to a method for optimizing the fermentative production of methionine and/or its derivatives comprising the steps of: c. culturing a recombinant microorganism wherein in said microorganism, the cobalamin-dependent methionine synthase activity and the methionine efflux are enhanced, in an appropriate culture medium comprising a fermentable source of carbon and a source of sulphur, and d. recovering methionine and/or its derivatives from the culture medium.
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