METHOD OF INCREASING EFFICIENCY OF THERAPY OF AUTOIMMUNE DISEASES, SUCH AS RHEUMATOID ARTHRITIS

摘要

FIELD: pharmaceutics.;SUBSTANCE: group of inventions is disclosed to reduce undesirable reaction of immunosuppressive drugs for treating autoimmune diseases. There are presented: pharmaceutical composition containing iguratimod or its salt and one or more immunosuppressive agents selected from nucleic acid synthesis inhibitors (e.g., methotrexate) or steroid anti-inflammatory drugs (e.g., prednisolone), device and kit of above purpose.;EFFECT: technical result consists in reduction of hepatocellular damage and elimination of reticulocytopenia caused by said immunosuppressants.;12 cl, 5 tbl, 9 ex