THERAPEUTIC AGENTS FOR REGULATING SERUM PHOSPHORUS LEVEL

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents a method of treating chronic kidney disease-mineral and bone disorder (CKD-MBD) in a patient receiving hemodialysis, wherein said method involves administering to patient a composition containing a compound, including Ac-c(C)arrrar-NH₂ (SEQ ID NO: 3), and a pharmaceutically acceptable excipient, where composition is administered as intravenous injection during a period beginning approximately 15 minutes before completion of haemodialysis and ending approximately 3 hours after hemodialysis, and where said administering allows to efficiently maintain post-hemodialysis serum phosphorus level below serum phosphorus level prior to hemodialysis during a period, of at least approximately 6 hours after dialysis.;EFFECT: invention allows to mitigate post-dialysis rebound of serum phosphorus level.;7 cl, 3 dwg, 4 tbl, 2 ex