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METHOD FOR DETERMINATION OF AUTHENTICITY AND QUALITY OF PERFORATE ST JOHN'S-WORT (HYPERICUM PERFORATUM L.)

机译:贯叶连翘(Hypericum perforatum L.)的真实性和质量的测定方法

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention relates to method for determining quality and authenticity of medicinal raw material of St John's-wort (Hypericum perforatum L.). The method consists in the following: water-alcohol extract of Hypericum perforatum L. herb is prepared, and analysed by method of high performance liquid chromatography. After that, concentration of rutin and hyperforin (mmol/l) is determined and used as basis for calculation of their content in Hypericum perforatum L, ratio of rutin to hyperforin is determined, and its value equal to 0.8-1.2 testifies to authenticity and quality of St John's-wort (Hypericum perforatum L.).;EFFECT: invention makes it possible to increase reliability in determination of authenticity and quality of medicinal raw material.;3 tbl
机译:技术领域本发明涉及确定圣约翰草(Hypericum perforatum L.)的药用原料的质量和真实性的方法。该方法包括:制备贯叶连翘的水醇提取物,并用高效液相色谱法进行分析。之后,测定芦丁和金丝桃素的浓度(mmol / l),并作为计算其在贯叶连翘中含量的基础,确定芦丁与金丝桃素的比例,其值等于0.8-1.2,证明了其真实性和质量。效果:发明使得增加确定药物原料的真实性和质量的可靠性成为可能。3 tbl

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