DENTAL PHYTOFILMS FOR TREATMENT OF PERIODONTAL AND ORAL MUCOSA INFLAMMATORY DISEASES

摘要

FIELD: pharmacology.;SUBSTANCE: the agent for the treatment of periodontal and oral mucosa inflammatory diseases is made as a film and comprises of herbal extracts as active ingredients and a film former, a plasticiser, an essential oil, and purified water as auxiliaries. It is characterised that it additionally contains a sangviritrin as an active substance, an oily extract of Calendula flowers and Achillea grass in a ratio of 1:1 and an Echinacea dry extract as extracts of medical plants, a hydroxyethylcellulose and glycerol as a plasticiser and film former, respectively, and additionally cremophor RH-40 and sodium saccharinate as auxiliaries and a peppermint oil as the essential oil at the following ratio, wt %: Sanguiritrin - 0.05, hydroxyethyl cellulose - 2.0, glycerol - 3.0, oil extract of Calendula and Achillea - 1.0, dry extract of Echinacea - 1.0, Cremophor RH-40 - 1.0, sodium saccharinate - 0.1, peppermint oil - 0.1, purified water - up to 100.0.;EFFECT: dental phytofilms are convenient and hygienic to use, have a good fixation on the lesion of the oral mucosa and hard tooth tissues When they are applied, the dose accuracy, prolonged yield of biologically active substances and constant drug concentration are maintained for a long time The films have a high adhesive ability to wet and hard tissues of the oral mucosa.;3 tbl, 5 ex