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METHOD FOR PREDICTING EFFICIENCY OF TREATING PATIENTS WITH CERVICAL CANCER RECURRENCES

机译:预测宫颈癌复发患者的治疗效率的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to haematological research in oncogynecology, and can be used in patients with cervical cancer recurrences to evaluate effectiveness of anti-tumour treatment and predict tumour process course. Essence of the invention consists in the following: after each course of polychemotherapy standard deviation of volume of neutrophils - SDVNe, lymphocytes - SDVLy and monocytes - SDVMo is determined in peripheral blood, values of coefficients SDVNe×SDVLy/100, SDVNe×SDVMo/100 and SDVLy×SDVMo/100 are calculated, and if values of each of the said coefficients are lower than 3.5, positive effect of anti-tumour therapy and favourable prognosis are predicted, if values of the coefficients are higher than 3.5, low efficiency of treatment and negative prognosis of disease course are predicted. The claimed invention is characterised by high self-descriptiveness, simplicity of implementation, possibility of multiple repetition of the test and does not require special financial expenditures.;EFFECT: method makes it possible to realise selection of the most rational method of anti-tumour impact and minimise development of a number of side effects, including depression of haematopoiesis, in due time.;1 tbl, 2 ex
机译:技术领域本发明涉及医学,即涉及妇科的血液学研究,可用于宫颈癌复发患者以评估抗肿瘤治疗的有效性并预测肿瘤的进程。本发明的实质在于:在多化学疗法的每个过程之后,在外周血中测定中性粒细胞-SDVNe,淋巴细胞-SDVLy和单核细胞-SDVMo的体积的标准偏差,系数SDVNe×SDVLy / 100,SDVNe×SDVMo / 100的值计算SDVy和SDVLy×SDVMo / 100,并且如果每个所述系数的值小于3.5,则预测抗肿瘤治疗的积极效果和良好的预后,如果系数的值大于3.5,则治疗效率低。并预测疾病进程的阴性预后。所要求保护的发明的特征在于高自我描述性,实施简单性,可以多次重复测试并且不需要特殊的财务支出。效果:该方法可以实现选择最合理的抗肿瘤影响方法并在适当的时候将包括血红细胞生成抑制在内的许多副作用的发生降到最低。; 1 tbl,2 ex

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