METHOD FOR TREATMENT OF GLAUCOMOUS OPTIC NEUROPATHY BY MEANS OF TRANSPLANTATION OF 3D CELLULAR CULTURE OF MULTIPOTENT MESENCHIMAL SCLERAL SULCUS STEM CELLS

摘要

FIELD: medicine.;SUBSTANCE: method involves application of multipotent mesenchymal stem cells (MMSC), obtained from allogeneic fragments of the human cadaver eyes scleral sulcus. 3D cell spheroids, 1000 cells in each spheroid, are created from these cells. 250 to 500 spheroids in 1 ml of a sterile 0.9% solution of sodium chloride are administered once parabulbarically.;EFFECT: method allows to improve and stabilise visual functions, to provide anti-apoptotic action, to prevent involvement of intact ganglion retinal cells in the apoptosis process due to a prolonged and stable secretion of neurotrophic factors by 3D-cell spheroids of multipotent mesenchymal stem cells.;2 ex