首页> 外国专利> METHOD FOR DETERMINATION OF CHEMOTHERAPY DURATION AFTER SURGICAL TREATMENT OF RESPIRATORY ORGANS TUBERCULOSIS IN CHILDREN AND ADOLESCENTS

METHOD FOR DETERMINATION OF CHEMOTHERAPY DURATION AFTER SURGICAL TREATMENT OF RESPIRATORY ORGANS TUBERCULOSIS IN CHILDREN AND ADOLESCENTS

机译:测定儿童和青少年呼吸器官结核的化学治疗后持续时间的方法

摘要

FIELD: medicine.;SUBSTANCE: after surgical treatment of respiratory organs tuberculosis in children and adolescents, pathohistological examinations of the operating material are carried out and the degree of inflammatory process activity, as well as the degree of the tuberculosis complex mycobacteria growth is determined. The presence of complications in the postoperative period, unavoidable adverse reactions to chemotherapy, the degree of residual changes in lungs and/or intrathoracic lymph nodes is also determined. At the level of surgical intervention, no more than two segments, absence of signs of inflammatory process activity or slight activity in the surgical material, absence of tuberculosis complex mycobacteria growth, absence of complications in the postoperative period, absence of adverse reactions to chemotherapy, absence or minor residual changes in lungs and/or intrathoracic lymph nodes, chemotherapy duration of three months is prescribed. With the same indicators, but with at least two additional indicators concerning the volume of surgical intervention either more than two segments, or combined resections, or intrathoracic lymph nodes removal, or pleurectomy, moderate or pronounced activity of the inflammatory process, detected growth of tuberculosis complex mycobacteria, development of complications in the postoperative period and development of adverse reactions to chemotherapy, chemotherapy duration of six months is prescribed.;EFFECT: reduced number of disease relapses and exclusion of unreasonably long courses of chemotherapy in children and adolescents.;1 dwg
机译:领域:药物;研究对象:对儿童和青少年的呼吸器官结核病进行手术治疗后,对手术材料进行病理组织学检查,确定炎症过程的活动程度以及结核病复杂性分枝杆菌的生长程度。还确定了术后并发症的存在,不可避免的化疗不良反应,肺部和/或胸腔内淋巴结残留改变的程度。在外科手术的水平上,不超过两个部分,在手术材料中没有炎症过程活动的迹象或轻微的活动,没有结核复杂的分枝杆菌生长,术后没有并发症,没有对化疗的不良反应,如果肺和/或胸腔内淋巴结不存在或有微小残留变化,则需化疗三个月。具有相同的指标,但至少有两个有关手术干预量的其他指标,包括两个以上的部分或联合切除,胸腔内淋巴结切除或胸膜切除术,炎症过程的中度或明显活动,检测到的结核生长复杂的分枝杆菌,术后并发症的发生和对化疗的不良反应的发生,化疗的持续时间为六个月。效果:减少疾病的复发次数并排除儿童和青少年不合理地漫长的化疗过程; 1 dwg

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