Acanthospermum hispidum composition for the treatment of cancer and methods for its manufacture

摘要

This invention relates to the field of cancer management, and in particular to the field of phytomedicine and nutraceutical composition for management of cancer, control of viral, bacterial and fungal infections, as well as other associated illnesses. This invention also pertains to the method of controlled, ecologically self-sustainable continuous horticulture combined with aquaculture (aquaponics system), for the described herbal plants and to the method for manufacturing the end products, both methods as per applicable ISO 14698 series and ISO-14644 series standards, EU GMP annex 1 and pharmacological Good Manufacturing Practice. The present application focuses primarily on Acanthospermum hispidum DC and on Solidago Canadensis L., and on their efficacy as anticancer agents, whereby 100% aqueous extract of Acanthospermum hispidum DC acts as immunomodulator possibly through initial vacuolisation followed by shrinkage of the cells and ultimately necrosis of the cells, and 100% aqueous extract of Solidago Canadensis L. exhibits the presence of cinnamoyl quinic acid that appears to cause the DNA groove binding thus preventing the formation of clumps of proteins which can distort the B-form double helix.