A procarbazine hydrochloride formulation

摘要

A pharmaceutical capsule comprises only procarbazine hydrochloride and a mixture of coprocessed corn starch and pregelatinised starch. Preferably, the weight ratio of procarbazine hydrochloride to the mixture of co-processed corn starch and pregelatinised starch is approximately 1:2, wherein preferably the capsule has a total weight from 220 to 280mg and a fill weight from 162 to 198mg. Preferably, the capsule comprises approximately 58mg of procarbazine hydrochloride.