首页> 外国专利> MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE

MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE

机译:MR影像学诊断性神经疾病

摘要

Disclosed is a compound represented by formula (1) or a salt thereof, formula (1) : wherein X is a residue of a compound having activity of binding to at least one member selected from the group consisting of amyloid ² proteins, tau proteins, ±-synuclein, and TDP-43; m is an integer of 0 to 6; n is an integer of 1 to 5; and J is a group selected from the group consisting of wherein R 1 and R 2 are each independently a hydrogen atom, a fluorine atom, methyl, or trifluoromethyl; R 3 is trifluoromethyl or trifluoromethoxy; and p is an integer of 1 to 4, provided that m + n ‰¥ 5 when J is J-1, and m + n ‰¥ 7 when J is J-2 or J-3.
机译:公开了由式(1)表示的化合物或其盐,式(1):其中X是具有与至少一种选自淀粉状β蛋白,tau蛋白,±突触核蛋白和TDP-43的成员结合的活性的化合物的残基; m是0至6的整数; n为1〜5的整数。并且J是选自以下的组:其中R 1和R 2各自独立地为氢原子,氟原子,甲基或三氟甲基; R 3为三氟甲基或三氟甲氧基;并且p是1到4的整数,条件是当J为J-1时m + n≥5,而当J为J-2或J-3时m + n≥7。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号