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ADJUSTABLE ENDOLUMENAL MITRAL VALVE RING

机译:可调式腔内肺动脉瓣环

摘要

Excessive dilation of the annulus of a mitral valve may lead to regurgitation of blood during ventricular contraction. This regurgitation may lead to a reduction in cardiac output. Disclosed are systems and methods relating to an implant configured for reshaping a mitral valve. The implant comprises a plurality of angled struts with rotatable screw and adjustable restraint, and anchors for tissue engagement. The implant is compressible to a first, reduced diameter for transluminal navigation and delivery to the left atrium of a heart. The implant may then expand to a second, enlarged diameter to embed its anchors to the tissue surrounding and/or including the mitral valve. The implant may then contract to a third, intermediate diameter, by rotating the screw and adjusting the restraint along a pair of adjacent struts, thus pulling the tissue radially inwardly, thereby reducing the mitral valve and lessening any of the associated symptoms including mitral regurgitation.
机译:二尖瓣环过度扩张可能会导致心室收缩期间血液反流。这种反流可能导致心输出量减少。公开了与被配置用于重塑二尖瓣的植入物有关的系统和方法。植入物包括多个带有可旋转螺钉和可调节约束装置的成角度的支柱,以及用于组织接合的锚固件。植入物可压缩至缩小的第一直径,以进行腔内导航并输送至心脏的左心房。然后,植入物可以膨胀到第二扩大直径,以将其锚固件嵌入围绕和/或包括二尖瓣的组织。然后,通过旋转螺钉并沿着一对相邻的支撑杆调节约束,植入物可收缩至第三中间直径,从而向内径向拉动组织,从而减少二尖瓣并减轻包括二尖瓣反流在内的任何相关症状。

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