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PROTECTIVE VACCINE AGAINST STAPHYLOCOCCUS AUREUS BIOFILMS COMPRISING CELL WALL-ASSOCIATED IMMUNOGENS

机译：包含细胞壁相关免疫原的金黄色葡萄球菌生物膜保护性疫苗

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摘要

Vaccine formulations effective against Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA) are disclosed, as well as methods of using the vaccine formulations in the treatment, prevention and prophylaxis of Staphylococcus aureus infections in a subject.

机译：公开了对金黄色葡萄球菌有效的疫苗制剂，包括耐甲氧西林的金黄色葡萄球菌（MRSA），以及使用该疫苗制剂在受试者中治疗，预防和预防金黄色葡萄球菌感染的方法。

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公开/公告号EP2344189B1

专利类型
公开/公告日2018-05-30

原文格式PDF
申请/专利权人 UNIVERSITY OF MARYLAND BALTIMORE;THE ARIZONA BOARD OF REGENTS A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND BEHALF OF;
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申请/专利号EP20090818291
发明设计人 SHIRTLIFF MARK E.;O MAY GRAEME;LEID JEFF;
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申请日2009-09-23
分类号A61K39/085;A61K38/48;A61P37;A61P31/04;A61K38/47;C07K14/31;
国家 EP
入库时间 2022-08-21 13:19:25

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7. Impact of Cell Substratum Adhesion Pattern and Cluster Spatial Distribution on the Development of Staphylococcus aureus Biofilm under Physiologically-Relevant Shear Rates [D] . Ajayi, Opeyemi O. 2018

8. The Extracellular Matrix of Staphylococcus aureus Biofilms Comprises Cytoplasmic Proteins That Associate with the Cell Surface in Response to Decreasing pH [O] . Lucy Foulston, Alexander K. W. Elsholz, Alicia S. DeFrancesco, 2014

9. Immunoglobulins to Surface-Associated Biofilm Immunogens Provide a Novel Means of Visualization of Methicillin-Resistant Staphylococcus aureus Biofilms▿ [O] . Brady, Rebecca A., Leid, Jeff G., Kofonow, Jennifer, 2007

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