PROMOTING EPITHELIAL REGENERATION POST TONSILLECTOMY USING HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR

摘要

Compositions and methods for promoting epithelial tissue regeneration to treat an oral or oropharyngeal wound, e.g., after tonsillectomy are disclosed. In particular, the invention relates to compositions comprising heparin binding epidermal growth factor like growth factor and their use in the treatment of an oral or oropharyngeal wound, e.g., post-therapy treatment to promote epithelial tissue regeneration in wounds, e.g., wounds resulting from surgical removal of tonsil tissue during tonsillectomy procedures, such as palatal, pharyngeal or lingual tonsillectomy. Additionally, HB-EGF can also be used after an adenoidectomy, a procedure sometimes combined with a tonsillectomy, to promote healing of wounds caused by surgical removal of adenoid tissue.